siRNA

Systemic RNAi in Western Corn Rootworm, Diabrotica virgifera virgifera

Li et al. recently reported how systemic RNAi occurred in the western corn rootworm (WCR), Diabrotica virgifera virgifera, one of the most important maize pests in North America and a model for understanding the mechanism of RNAi. Efficiency of RNA […]

RNAi-based therapeutics: Delivery is key and relevant to insects

Specific gene knockdown after exogenous small interfering RNA (siRNA) injection into humans and mammals holds great promise for therapeutic applications. But enthusiasm  waned and some predict its demise because of the manifold problems in delivering the technology. A new review […]