Postdoc – Mosquito Molecular Genetics – University of Maryland

David O'Brochta Director

David O’Brochta, Ph.D., University of Maryland College Park

Applications are invited for a Postdoctoral position currently available in the laboratory of David O’Brochta at the Institute for Bioscience and Biotechnology Research (IBBR)/University of Maryland in Rockville, MD. The successful candidate will be responsible for executing and managing an NIH funded project involving the genetic analysis of Anopheles mosquitoes using newly developed gene- and enhancer-trapping technologies. This is a one-year appointment with the possibility of a second year depending on progress and performance. Duties will include designing and executing genetic crosses for the purposes of identifying genes and enhancers relevant to the vectoral capacity of Anopheles mosquitoes, molecular genetic analysis of genes and enhancers identified during genetic screens, using the Gal4/UAS system to investigate the roles of genes of interest in specific cells and tissues during Plasmodium infection, supervising junior technical staff assigned to the project, preparing data for reporting and publication, presenting data to colleagues.

Figure 8.jpg

This is a Gal4 enhancer trap line in which Gal4 is expressed specifically in a number of tissues that play important roles during Plasmodium infection. This and similar lines with useful patterns of Gal4 expression are being used to ask questions about the roles of various genes in specific cells and tissues during a Plasmodium infection. We are particularly interested in the late phases of Plasmodium infection.

Ph.D. in Genetics, Molecular Genetics, Entomology or related field. Knowledge of and experience working with insects (preferably mosquitoes) will be highly advantageous. Knowledge and experience with molecular genetic technologies including basic cloning technologies and gene analytics required. Must be willing and able to work with and around insects (mosquitoes), laboratory mice and, human and animal blood.

Knowledge of and experience working with Plasmodium parasites preferred. Knowledge and experience of forward genetic technologies (mutagenesis, gene-traps, enhancer traps) genetic screens and other genetic approaches preferred.


Inquiries can be sent to David O’Brochta (

Applications must be made here to be considered for the position.


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