Serratia marcenscens. Image credit

Vertical and Horizontal Transmission in Paratransgenic Anopheles Mosquitoes

Wang et al. (2017) report results in Science that appear to make significant progress toward solving one of the more challenging problems associated with using paratransgenic approaches for sustainable insect phenotype modification. Paratransgenesis is an interesting concept involving the genetic […]

A selfish gene (blue) spreading through a mosquito population

Driving Transgenes with Disassortative Mating

Pike et al. (2017) in a recent publication in Science describe a novel approach to rapidly increasing transgene frequencies in mosquito populations (‘gene drive’) for the purposes of reducing or eliminating Plasmodium transmission. There is increasing attention within the insect […]

Cas9-Mediated Gene-Drive In Mosquitoes

Gantz and Bier who demonstrated the fundamental principles of a Cas9-based gene drive system using Drosophila melanogaster in a publication earlier this year have recreated that system in the mosquito Anopheles stephensi with the help of collaborators.  Gantz et al. […]

Anopheles stephensi Image from: Vectorbase

Towards a Medea Drive System in Anopheles Mosquitoes

Germ-line specific promoters are useful to insect biologists and Biedler and colleagues (2015) in a just-published paper in G3-Genes|Genomes|Genetics report their efforts to identify, isolate and test maternal germline-specific genes and promoters in the Asian malaria vector, Anopheles stephensi. “We […]