silencing

standard Carbon Quantum Dots for dsRNA Delivery

Das et al. (2015) in Applied Materials & Interfaces compare chitosan, silica and carbon quantum dot nanoparticles as dsRNA delivery platforms for silencing genes in larval mosquitoes. Direct injection of dsRNA into the hemocoel of insects has  been somewhat effective […]

standard Plastid Mediated RNAi: A Novel Insecticidal Tool

Recently, Zhang et al demonstrated a robust and promising way of controlling the devastating solanaceous crops insect pest, Colorado potato beetle (Leptinotarsa decemlineata; CPB), using a modified strategy for delivering plant mediated RNAi. Increasing insect herbivores’ resistance to plant defense mechanisms […]

standard RNAi-based therapeutics: Delivery is key and relevant to insects

Specific gene knockdown after exogenous small interfering RNA (siRNA) injection into humans and mammals holds great promise for therapeutic applications. But enthusiasm  waned and some predict its demise because of the manifold problems in delivering the technology. A new review […]

Feeding Pea Aphid, Acyrthosiphon pisum

standard RNA Silencing in Plants to Fight Aphids

Aphids feed from the plant phloem sap and are responsible for large damage on crops by either weakening the plant or transmitting plant viruses that circulate in the sap. Can we use transgenic plants to limit aphid negative impact on […]