RNA

CRISPR/Cas9 Knock-in Technology

Cas9 Against RNA Targets In Vivo

Price et al (2015) have recently published a paper in PNAS in which they report that Cas9 can be used as a RNA-targeting system. Clustered, regularly interspersed, short palindromic repeats-CRISPR associated (CRISPR-Cas) systems are a diverse collection of adaptive immune […]

Cas9 with functional domains highlighted in relation to target DNA and guideRNA

CRISPR/Cas9 for RNA Cleavage

The CRISPR/Cas9 system is quickly becoming the most versatile method for modifying DNA targets, but researchers seeking equivalent control against RNA transcripts have been left behind. In a new paper by O’Connell et. al, (2014) the authors describe a clever […]