resistance

A recent scheme showing the consequences of distorting mosquito sex ratios using a "precision" drive system.

standard Strategies for Driving Out Invasive Species

Prowse et al. (2017) present their modelling work in the Proceedings of The Royal Society B on various different CRISPR/Cas9-based gene drives aimed at suppressing populations of exotic vertebrate species on islands (focusing on mice (Mus musculus)).  The issues addressed […]

User-designed molecular scissors.

standard Dynamics of Gene Drive Resistance – Lab Cage Trials

In their current pre-publication Hammond et al investigate the emergence of resistance to a homing-based gene drive designed to disrupt a gene essential for female Anopheles gambiae fertility. In recent years, there has been much theoretical design and modeling work […]