University at Buffalo
Buffalo, New York USA
Areas of Expertise:
Genetics, Biochemistry, Gene regulation, enhancers, Gene regulatory networks, Data mining
Drosophila melanogaster, Aedes aegypti
As a Computer Science graduate and a PhD candidate in Biochemistry, I am interested in both computational biology and wet-lab genetics/molecular biology.
In collaboration with the Sinha lab in the Department of Computer Science at the University of Illinois at Urbana Champaign (http://www.sinhalab.net/sinha-s-home), we have developed a computational pipeline to predict cis-regulatory modules (CRMs) genome-wide in evolutionarily diverged dipteran species such as the honey bee, malaria mosquito, wasp, and the flour beetle, by using enhancers identified experimentally in Drosophila melanogaster.
Currently, I am interested in the gene regulatory circuitry for central nervous system specification in the fruit fly and the yellow fever mosquito (Aedes aegypti), and am trying to understand the mechanisms of enhancer action for the same genes in both species through a thorough analysis of the genes and their CRMs within each species' CNS-specification network.