Kallare Arunkumar
Faculty Member
Centre for DNA Fingerprinting and Diagnostics
Hyderabad, Telangana India

Areas of Expertise:
Insect genetics, genomics, evolutionary biology, phylogenetics

Research Organisms:
Bombyx mori, Antheraea species, Spodoptera species


Research Focus:

During the last one decade, research in the silkworm, Bombyx mori has witnessed explosive developments which include unveiling of complete genome sequence; availability of large amount of transcirptomics resources through ESTs, microarray and RNAseq; high density linkage and physical maps; map-based cloning; well-established piggyBac mediated transgenics; TALENs based gene disruption systems; and identification of critical genes for proliferation of baculovirus. The concomitant advancements in other insects such as Drosophila, Honeybee, Mosquito, and Tribolium, particularly in understanding sex-determination mechanisms, microRNA functions, molecular mechanisms of immune response pathways and RNAi-based analysis of gene functions, provide impetus to build silkworm as a basic lepidopteran model system on one hand and to improve economic returns of the sericulture industry on the other. Significantly, the available genetic and genomic research repertoire of the silkworm, B. mori provides the required resources to address various biological questions in economically important native Indian wild silkmoths that have remained largely unexplored. In addition, developing a lepidopteran model system can spin off genetic information as well as molecular biological tools to be applied in the management of lepidopteran pests of Indian agriculture. With this background we are interested in studying following research topics in our laboratory:

Sex determination pathway of silkmoths
Sex chromosome evolution
Insect immune response