Areas of Expertise:
transcriptional regulation, development, cell cycle control, systems biology
Our research focuses on understanding the mechanisms of transcriptional regulation in the context of Drosophila development. We utilize genetic and molecular biological approaches to study the role of enhancers in regulation of signaling and patterning circuits, including insulin signaling, retinoblastoma-mediated control of growth related genes, and chromatin-modulating complexes important for development. Evolutionary perspectives lead us to consider how these processes are active in non-model insects, as well as vertebrates.