In their recent paper in G3: Genes|Genomes|Genetics, Li et al. describe a highly efficient protocol for the generation of stable knockout lines using CRISPR/Cas9. The ability of effectively targeting and disrupting gene function is essential for gene functional analysis studies […]
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The Journal of Responsible Innovation has published a special issue entitled: Roadmap to Gene Drives: Research and Governance Needs in Social, Political, and Ecological Context. This is a collection of 13 papers and is the outcome of workshop held in […]
Four recently published papers on containment issues concerning genetically modified insects. 1. Recommendations for Laboratory Containment and Management of Gene Drive Systems in Arthropods. Benedict Mark Q., Burt Austin, Capurro Margareth L., De Barro Paul, Handler Alfred M., Hayes Keith […]
Li and Handler (2017) have recently reported using CRISPR/Cas9 to make a temperature-sensitive transformer-2 (tra-2) allele in the pest species Drosophila suzukii by mutating the nucleotides orthologous to the Drosophila melanogaster tra-2ts2 allele. This study demonstrates an important proof of […]
Advances in CRISPR/Cas9 Genome Editing in Drosophila Lead the Way for Applications in Other Insects.
In the January edition of FlyBook (Genetics) Bier et al. review the recent advances in CRISPR/Cas technologies applied to the fruit fly, delving into the details of established and cutting-edge methods and their potential applications to future studies in this […]
2018 IGTRCN Technical Short Course on Insect Genetic Technologies: Theory and Practice July 22 – 27, 2018 The Insect Transformation Facility Institute for Bioscience and Biotechnology Research University of Maryland College Park Applications by April 2, 2018 (24 seats available) […]
Mysore et al. recently reported in the Malaria Journal their successful development of a number of Anopheles larvicides consisting of yeast expressing specific siRNAs. RNAi has attracted considerable attention as a pest control tool, particularly in the agricultural space. In […]
Engineered synthetic species-like barriers were recently described by Maselko et al (2017) in Nature Communications and the work has interesting implications for genetic control strategies and gene drive containment. There is an ever-increasing interest in manipulating natural populations using genetic […]
In early 2018 Mary Ann Liebert, Inc. will begin publishing The CRISPR Journal. Their publishing interests are broad and manuscripts are being solicited for inclusion in their inaugural issue in early 2018. This is from the journal’s website: “The rampant […]
The intense selection pressure that CRISPR/Cas systems placed on viruses has resulted in the evolution of a number of anit-CRISPR proteins meant to silence this bacterial ‘immune system’. Dong et al (2017) report on a database they constructed that aggregates […]