Nathaniel Grubbs

Anopheles gambiae

standard Gene Drive In Anopheles gambiae

Hammond et al.’s just published paper in  Nature Biotechnology is the second paper in a month demonstrating effective CRISPR-based gene drive in a mosquito vector of malaria.  In this case the main malaria vector in Africa, Anopheles gambiae. Gene drive […]

standard CRISPR with Independent Transgenes or Mutagenic Chain Reaction for Creating Homozygotes in Lab?

In fall of 2014, two publications came from George Church’s group (Esvelt et al., 2014; Oye et al., 2014) postulating on the potential for the CRISPR/Cas9 system to be used as an autonomous gene drive for various pest management goals. […]