David O'Brochta

Cas9 Mutagenesis in Houseflies Confirms Male Determining Factor Identification

Sharma et al. (2107) report in a recent issue of Science the identification of a male determining factor in the housefly Musca domestica and provide convincing reverse genetic confirmatory evidence using dsRNA-mediated gene silencing and Cas9-mediated mutagenesis. Alternative splicing of […]

Western Corn Rootworm, Diabrotica virgifera virgifera, germline transformation.

Chu and colleagues in a recently published paper in Insect Molecular Biology describe their successful efforts to deploy transposon-based technologies in the economically important beetle, Diabrotica virgifera virgifera, and it is an interesting case study in how to develop genetic […]

Call for Sweeping Moratorium on Gene Drive Research and Application at UN Biodiversity Conference

The UN Convention on Biological Diversity is currently holding their Biodiversity Conference in Cancun, Mexico.  Monday 160 organizations from six continents released a statement calling for a global moratorium on all work on gene drives, including laboratory research.   The […]