Technology Topics

aedes_aegypti

standard More Aedes Editing – More Insights

In a recent PLoS One paper, Dong et al. (2015) describe their successful attempts to edit the genome of Aedes aegypti using CRISPR/Cas9. As proof of principle, they aimed to excise a portion of a transgene that codes for enhanced […]

Cas9 + sgRNA

standard Modified Guide-RNAs Enhance CRISPR Editing

Hendel et al. (2015) have shown in Nature Biotechnology that certain chemical modifications to guide RNAs can enhance mutagenesis frequencies of the CRISPR/Cas9 system.  Clearly, these types of enhancements, should they pan out to be effective beyond human cells, could […]

Mouse

standard Microinjection independent genome engineering

Takahashi et al. (2105) describe a microinjection independent genome engineering method for mice that is an interesting innovation that seeks to address technical challenges associated with the creation of transgenic and genetically modified mice that have good analogs in insect […]

Network Announcements

EntomopathoCongress

standard 5th International Entomopathogens and Microbial Control Congress

“The Fifth International Participated Entomopathogens and Microbial Control Congress” Ankara, Turkey   September 9-11, 2015. Entomopathogens form an interesting area of research in pest management as being one of the most important tools of environmetally-friendly, applicable and effective pest management strategies […]

Positions Available

standard New England Biolabs position

Research Scientist I – DNA Enzyme Division – Full Time – Job Code 1032AG   The DNA Enzymes Division of New England Biolabs invites applicants for the position of Research Scientist I.  The successful applicant will work within a dynamic […]

Knowledgebase

FlyFacility, Cambridge University.  A insect genetic technologies service provider and resource

standard Fly Facility, University of Cambridge, UK

Insect Genetic Technologies Service Provider – Drosophila – Non-commercial Fly Facility, University of Cambridge, UK – http://www.flyfacility.gen.cam.ac.uk Our Drosophila microinjection service is available to fly researchers throughout the European Union. We can inject flies (including non-melanogaster Drosophila species) for P-element/piggyback […]

Service Providers

standard Insect Genetic Technologies Service Providers

Insect Genetic Technology Service Providers If you would like to add to this list use the “Make a Submission” button and select “Knowledgebase” For insects other than Drosophila melanogaster Non-Commercial The Institute for Bioscience and Biotechnology Insect Transformation Facility, University […]

CRISPRWebResources

standard CRISPR/Cas Web Resources

Web Resources for design and planning of CRISPR/Cas9 studies from Bassett and Liu (2014) CRISPR/Cas9 and Genome Editing in Drosophila. J. Genetics and Genomics 41, 7-19 doi.10.1016/j.gg.2013.12.004 Name Link Brief description Reference Drosophila CRISPR web resources OxfCRISPR (Liu Lab) http://www.oxfcrispr.org/ […]

CRISPRsDrosophila

standard CRISPR In Drosophila

Comparison of CRISPR genome engineering studies in Drosophila from Bassett and Liu (2014) CRISPR/Cas9 and Genome Editing in Drosophila. J. Genetics and Genomics 41, 7-19 doi.10.1016/j.gg.2013.12.004 Reference Gratz et al., 2013 Bassett et al., 2013 Yu et al., 2013 Kondo and Ueda, 2013 […]