Technology Topics

standard Short-Half Life Cas9 Improves Mutagenesis

Reducing the half-life of Cas9 has some positive and unexpected impacts on the  efficiency of mutatgenesis, according Tu et al (2017) in a paper they just published in Scientific Reports. Tu et al were primarily interested in applying Cas9 mutagenesis […]

standard Rapid Generation of Hypomorphic Mutations

While CRISPR/Cas9 has made null mutations easier to obtained, Arthur et al (2017) describe a general method for creating hypomorphic mutations that should further enable our abilities to tune levels of gene expression to suite particular needs. Eliminating a gene’s […]

Network Announcements

standard New i5K Webinar Series!

i5k is hosting a new webinar series with presentations by representatives from genomic technology companies, databases and research groups.   Webinars will be 1 hour long, but presentations will be kept short enough to allow plenty of time for participants […]

standard CAMTech Symposium and Lunch at ICE2016

Public-Private Partnerships for Development of Next-Generation Pest Management Methods Wednesday, September 28, 2016 9:15 AM – 11:30 AM Convention Center – Room W314A The Center for Arthropod Management Technologies: Industry perspective Developing novel cell lines from selected pests Mechanisms of […]

Positions Available

Knowledgebase

standard Fly Facility, University of Cambridge, UK

Insect Genetic Technologies Service Provider – Drosophila – Non-commercial Fly Facility, University of Cambridge, UK – http://www.flyfacility.gen.cam.ac.uk Our Drosophila microinjection service is available to fly researchers throughout the European Union. We can inject flies (including non-melanogaster Drosophila species) for P-element/piggyback […]

standard Insect Genetic Technologies Service Providers

Insect Genetic Technology Service Providers If you would like to add to this list use the “Make a Submission” button and select “Knowledgebase” For insects other than Drosophila melanogaster Non-Commercial The Institute for Bioscience and Biotechnology Insect Transformation Facility, University […]

standard CRISPR/Cas Web Resources

Web Resources for design and planning of CRISPR/Cas9 studies from Bassett and Liu (2014) CRISPR/Cas9 and Genome Editing in Drosophila. J. Genetics and Genomics 41, 7-19 doi.10.1016/j.gg.2013.12.004 Name Link Brief description Reference Drosophila CRISPR web resources OxfCRISPR (Liu Lab) http://www.oxfcrispr.org/ […]

standard CRISPR In Drosophila

Comparison of CRISPR genome engineering studies in Drosophila from Bassett and Liu (2014) CRISPR/Cas9 and Genome Editing in Drosophila. J. Genetics and Genomics 41, 7-19 doi.10.1016/j.gg.2013.12.004 Reference Gratz et al., 2013 Bassett et al., 2013 Yu et al., 2013 Kondo and Ueda, 2013 […]