Technology Topics

Cas9 Orthologs with Minimal PAM Requirements

In their recent paper Chatterjee and colleagues (2018) describe a natural protospacer adjacent motif (PAM) plasticity of previously uncharacterized Cas9 endonuclease from Streptococcus canis (ScCas9).  Chatterjee et al (2018) report ScCas9’s affinity to minimal 5’-NNG-3’ PAM sequences and describe its accurate editing capabilities, […]

Precision-Guided Sterile Insect Technique

Right after the 2019 New Year, Kandul et al (2019) described a novel CRISPR-based technology which they termed as “precision guided sterile insect technique (pgSIT)”. The idea of traditional SIT was planted in 1930s, which uses radiation to induce sterility […]

A Multiple Gene Drive System

Yan & Finnigan, (2018) recently published a paper in Scientific Reports describing an artificial multi-locus gene drive system by using a single Cas9 and three guide RNA (gRNA) in the budding yeast Saccharomyces cerevisiae. Nuclease-based gene drives do not follow […]

Network Announcements

2019 IGTRCN Technical Short Course – Applications Open

2019 IGTRCN Technical Short Course on Insect Genetic Technologies: Theory and Practice July 21 – 26, 2019 The Insect Transformation Facility Institute for Bioscience and Biotechnology Research University of Maryland College Park Applications by April 1, 2019 (24 seats available) […]


INVITATION FOR 1ST INTERNATIONAL MOLECULAR PLANT PROTECTION CONGRESS-ADANA, TURKEY, APRIL 10-13, 2019 Dear Colleagues, Molecular approaches are currently among the most popular topics in biological sciences and provide many opportunities in the solution of various problems. We have witnessed […]

Positions Available

Postdoctoral Position James Lab UC Irvine

A postdoctoral scholar in the Anthony A. James lab is involved with active national and international research on novel methods for controlling the transmission of vector‐borne diseases. Developing genetic techniques to control the transmission of vector‐borne diseases, specifically malaria and […]