Technology Topics

New SpCas9 With Expanded Target Range

Nishimasu et al. (2018) recently reported in Science on their finds related to a new SpCas9 modification referred as SpCas9-NG that has an expanded target range. The authors directionally mutated the wild-type SpCas9 enzyme to achieve its relaxed preferences to the […]

Parallel Cloning by Site Specific Recombination

Blanco-Redondo and Langenhan (2018) report recently in G3 valuable improvements in the  φC31 system that enable the simultaneous targeted integration of two transgenes into distinct landing sites using a single source of  φC31 recombinase. The development of modern genetic engineering […]

Network Announcements


INVITATION FOR 1ST INTERNATIONAL MOLECULAR PLANT PROTECTION CONGRESS-ADANA, TURKEY, APRIL 10-13, 2019 Dear Colleagues, Molecular approaches are currently among the most popular topics in biological sciences and provide many opportunities in the solution of various problems. We have witnessed […]

IGTRCN 2018 Technical Workshop – July 22-27

2018 IGTRCN Technical Short Course on Insect Genetic Technologies: Theory and Practice July 22 – 27, 2018 The Insect Transformation Facility Institute for Bioscience and Biotechnology Research University of Maryland College Park Applications by April 2, 2018 (24 seats available) […]

Positions Available

PhD: sex conversion gene drives

A collaborative BBSRC funded PhD project is available with Prof Tracey Chapman (University of East Anglia) and Dr Philip Leftwich (Pirbright Institute) is available To use CRISPR/Cas9 gene editing to investigate the molecular pathways underpinning male/female sex determination, with the […]